From the capital city of La Rioja, driving south, National Route 38 leads to the town of Patquia, and after turning right on National Route 150,Talampaya Canyon service area is only 140Kms away.

Driving from Cordoba city, National Route 38 to La Rioja passes by Valle de Punilla and reaches Patquia; from there, a right turn on National Route 150 reaches the Talampaya Canyon service area. The total journey from Córdoba is approximately 520Kms.

Driving from Buenos Aires, the best option is to take National Route 9 to Córdoba city and then National Route 38, in the direction of La Rioja. When at Patquia, National Route 150 will lead you to Talampaya Canyon service area entrance. The total journey from Buenos Aires is approximately 1270Kms.

From San Juan and Ischigualasto the journey on National Routes 76 and 150 is little over 70Kms. long.